(2006 BSG)肝硬化腹水的管理指南

发布日期:
2006-09-25
英文标题:
(2006 BSG)Guidelines on the management of ascites in cirrhosis
出处:
Gut. 2006 Oct;55 Suppl 6:vi1-12.
摘要:

Ascites is a major complication of cirrhosis,1 occurring in 50% of patients over 10 years of follow up. The development of ascites is an important landmark in the natural history of cirrhosis as it is associated with a 50% mortality over two years and signifies the need to consider liver transplantation as a therapeutic option. The majority (75%) of patients who present with ascites have underlying cirrhosis, with the remainder being due to malignancy (10%), heart failure (3%), tuberculosis (2%), pancreatitis (1%) and other rare causes. The true prevalence and incidence of cirrhosis of the liver and its complications in the UK are unknown. Mortality from cirrhosis has increased from 6 per 100 000 population in 1993 to 12.7 per 100 000 population in 2000. Approximately 4% of the general population have abnormal liver function or liver disease and approximately 10–20% of those with one of the three most common chronic liver diseases (non-alcoholic fatty liver disease, alcoholic liver disease, and chronic hepatitis C) develop cirrhosis over a period of 10–20 years. With a rising frequency of alcoholic and non-alcoholic fatty liver disease, a huge increase in the burden of liver disease is expected over the next few years with an inevitable increase in the complications of cirrhosis. There have been several changes in the clinical management of cirrhotic ascites over recent years, and the purpose of these guidelines is to promote a consistent clinical practice throughout the UK.

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玫心
2020.10.20
回复
腹水是肝硬化的主要并发症,1 发生在50%的患者超过10年的随从。腹水的发展是肝硬化自然史中的一个重要里程碑,因为它与两年内50%的死亡率有关,表明有必要将肝移植作为治疗选择。多数 (75%)患有腹水症的患者有潜在的肝硬化,其余是由于恶性肿瘤(10%)、心力衰竭(3%)、结核病(2%)、胰腺炎(1%)和其他罕见的原因。在英国,肝硬化及其并发症的真实流行和发生率尚不得而知。肝硬化死亡率从1993年每10万人6人增加到2000年每10万人12.7人。大约 4% 的一般人群有异常的肝功能或肝病,大约 10-20% 的人患有三种最常见的慢性肝病(非酒精性脂肪肝病、酒精性肝病和慢性丙型肝炎)之一,在 10-20 年内发展为肝硬化。随着酒精和非酒精性脂肪性肝病发病率的上升,预计未来几年肝病负担将大大增加,肝硬化并发症的并发症也不可避免地增加。近年来,肝硬化的临床管理发生了一些变化,这些指南的目的是促进全英国的临床实践。
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梁莹莹
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英国胃肠病学会

英国胃肠病学会(The British Society of Gastroenterology,BSG)专注于提升英国胃肠病学医疗水平,其涉及内科、外科、病理、放射、科学、护理、营养等领域。指南可以按日期、及专科浏览。

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